Are Penicillin Allergies Being Overreported?
According to a recent study published in the journal Clinical Infectious Diseases, the majority of patients with reported penicillin allergy are not actually allergic when tested or challenged. Data have emerged showing beta-lactams to have multi-dimensional antibacterial effects, including enhancing bacterial killing by the innate immune system. This is especially important in the treatment of Staphylococcus aureus bacteremia. Therefore, penicillin allergy testing could significantly reduce future annual healthcare expenditures and should be a vital component of antimicrobial stewardship practice.
Have you ever encountered a patient who said they had a penicillin allergy, but after further investigation, didn’t?

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